Yeah, that is what my pdoc told me. It negates the effects of meds for a day or so. Something to do with GABA receptors in the brain.

I drink very occasionally now, hoping to stop completely. Alcohol makes me super depressed the day after I drink. This only happens with a bit more than a couple of drinks. Yesterday I had two beers, and I was fine. But I also have a problem with moderating my intake. I tend to drink way too much, usually. So it's better for me that I don't drink, and that has nothing to do with bipolar.

Also, I'm on Cymbalta and mixing it with alcohol is bad for the liver.