Good question. The brain can only use the resources we provided it. The best line I have heard is that 'what's good for the heart is good for the brain'. And there is a ton of literature and research on heart disease and I mean like a ton. Just don't believe everything you read fats are good for you um kay. And triggering the insulin response does seem to be implicated in heart disease. Not to mention that being bipolar means you have about a 30% increase in the rate of type II diabetes anyways. Some of it due to meds (antipsychotics), but also have been found to correlate in drug naive patients as well. I don't know too much about it but ketogenic diets (or a diet that induces ketosis) is when the brain is using ketone bodies as fuel instead of sugar? Which to me makes sense as sugars are pretty hard to find in nature year round, but protein and fats are abundant any time of year (I mean if we don't ship **** from Argentina so we can eat apples all year long). Sorry if I got excited love the topic!