A weak/moderate drink or two at most on a single day is fine, anything more and for the next week or two I'm depressed and unstable. I recently went to a wedding and drank three days in a row, three+ drinks each day, and I'm still feeling really down. Alcohol should only do that for a few days, so my guess is it either triggers depression in me or messes with how my meds (Lamictal, Lexapro) are working for me.