I've been taking Lamictal for the past few weeks. I'm trying to get down about 10 lbs and it sure is a little harder. That being said, I've changed my eating habits to accommodate (i.e. eating all of my calories before 6pm, counting my calories religiously, etc). I haven't had much of a weight gain problem. I also run about 15 miles a week, so that may be a contributing factor.