I think the tricyclics work on serotonin, norepinephrine, and dopamine, right? If so, that's basically like what I'm starting on now, with Zoloft (SSRI) and Wellbutrin (works on norepinephrine and dopamine). I was on Cymbalta (SNRI) and then Cymbalta and Wellbutrin, but had some Cymbalta side effects.

I'm on fairly low doses, but so far this combo is working OK for me. I've heard the tricyclics are very effective--hope it works for you!