So, night before last was my first night on Depakote. Holy Cow! Up all night long. Thought I was going to have a heart attack. Body felt like it had energy volts going through it. Scared me so bad. I thought it was supposed to make you tired! I called my pdoc and she said to stop taking it until I get down to 300mg of Lithium (one more week), and try again. She thought it might be the combo of all three at their current doses. God, I hate this. Anybody have that reaction?