I think effexor was the second med I tried..so not a last resort! It helped for a while, but events in my life at the time also helped lift my mood I think. I'm not that great at sticking to my meds though and started messing around with the dose as I felt I didn't need them anymore. After that it never seemed to have the same effect

When I was on it I don't really remember any side effects. But you certainly know about it if you are late taking it or miss a dose. Coming off of it is not easy! I probably wouldn't try it again purely because I don't want to go through stopping it again..

But when it worked it was a good med..hopefully it works well for you