Journeyman, I understand your question is more of how to talk with her without making her feel bad or stop taking her meds. Wow, tough question. I am a woman and sensitive about my weight...I am going to have to think about this and write later--if I come up with some ideas. I am thinking maybe buy her an article of clothing that fits right and compliment and encourage her to wear it. Maybe she will want to stop wearing the old clothes if she gets some positive reinforcement...? I know that does not solve the problem of getting her to lose the weight, but maybe it will get her to think about it.