I had a second opinion last week at the university hospital and they recommended I quit all my meds because they aren't working and to see what's "left of me" without the meds.

I'm now tapering off imipramine and Zyprexa - Imipramine currently from 250mg to 200mg and Zyprexa from 25mg to 20mg (well, we'd done that step six weeks or so ago, so not because of the second opinion but because 25mg is a very high dose and I was having side effects) and now to 15mg.

I hope it helps. It'll be a few months before I'm completely off them.