Yes, we all have changes in our life. It does suck when its
not a good change. But, I guess we can't always be the
same person, because we grow older, wiser,etc.

Friends come and go, relationships with other partners
begin or end.
People also change when they get sick and get depression. I really think it is meant to be, otherwise our
lives would be boring.

I hope this makes sense.
Take care,.