I took Pristiq ER 50 mg just 2 days ago for the fisrts time.
I couldn't tolerated. I had very bad heachaches. I couldn't sleep. I wanted to go to the ER ( was the middle of the night went got worse) but I decided to stay home, drinking a lot of water and wait. Now after 48 hours or so I am fine.

I am someone that have severe issues with regular anti depressed medication.

I have not high blood pressure. I stop taken. But this is just me.

I hope you all are doing well. Good topic. Thanks.