I think with 25-50 mg you should be fine. I take it for insomnia occasionally and don't see any difference in my appetite.

When i was at 200 - 400 it made me eat at night like crazy. Fast carbs and then more fast carbs. Craving for those was really unbelievable. It happened 30-60 minutes after taking med.

Also when tired, people tend to eat fast carbs. With seroquel i was always tired and i think that's one reason.

Gained 30 pounds in one year.