I'm frustrated with Seroquel. At higher doses it didn't really do anything positive for me. When I began taking Geodon I stopped taking Seroquel - and experienced horrible insomnia and nausea. So it seemed that the Seroquel wasn't really doing anything for me, but when I stopped taking it I had bad withdrawal effects.

So, I decided the best thing to do is take 50mg at bedtime to help me sleep (I take immediate release Seroquel). For the first two weeks, I slept really well and felt very good. Unfortunately, I've noticed that this week my sleep isn't nearly as good...takes a long time to fall asleep & I awaken really early.

As for any other positive effects (lessening delusional thinking), at a low dose Seroquel doesn't do anything helpful. But then...it didn't really do anything helpful at the higher dose, either. Maybe a very slight anxiety reduction - sometimes.

That's why I started taking Geodon - which is helpful. At least, so far.