Oh, yes. It can just come out of the blue. It's not you - it's the anxiety. Stuff can only stay buried in our bodies for so long, and they have to be expressed.
I have tried lots of stuff: vistaril (nope), xanax (yes - but it is addictive for me), and effexor, which finally addressed the depression and anxiety.
I also have big hormonal problems which make the anxiety and panic worse.
Work with your doctor, keep a record of your experiences, and remember that it can get better.
pc