I can tell you that menopause has been the best thing that ever happened to my bipolar. It's still bad and still treatment resistant and severe and ugly in various ways but it is not the way it used to be. So there is hope, eventually. I was very fortunate to go into menopause early and then to have a hysterectomy which further sped up the process. If I'm not through it then I'm very close and even this episode from hell is apparently better than my really bad ones in the past and that's the major difference (I have no good memory to compare to but my therapist swears I've been worse and I believe him).