Hi wanderlust90, I've experienced agitated depression for most of my life. Most p-docs have diagnosed me with Bipolar Disorder 2 and call the agitated depression 'dysphoric mania'. SSRI's used to help a great deal, but in the past 3 years the full dose of an SSRI began to cause an awful, severe anxiety for me. So I now take only half a clinical dose of an SSRI (Lexapro).

Two meds have been most helpful for my agitated depression/dysphoric hypomania in the past few years. Those two are Inderal (a betablocker) and Geodon, at a low dose.