Are you on regular release Seroquel or XR? I usually take XR which takes hours to put me to sleep (it's not the best for sleep for me anymore). In the hospital they only had immediate release and that knocked me out within an hour but that only lasted a week or so and then I was back to not getting to sleep easily. (that probably won't happen to you, I'm on a lot of it and it hasn't been working that well for a while now)