It's funny you ask, because this morning I skipped my usual large coffee and went straight to work. I work in a school, so it is almost impossible to get up a cup while you are there. By lunchtime, I had a terrible headache, and by the time I got home I felt sick to my stomach. You'd think I wouldn't be so dependent on one coffee per day, but I guess you can be. Aside from that, I often feel a great deal of anxiety after drinking a cup and have to take my anxiety medicine to calm down. If you think about it, it doesn't make sense to drink coffee, as delicious as it is.