I was on 2 this summer but had muscle stiffness and uncontrolled oral motor movements from the 2nd so had to come off it. Now I still probably need a 2nd but most of the ones my insurance covers are likely to cause the same syndrome that I had to come off the one this summer for. I may be going on Rexulti or cariprazine, both of which are very new, because my psychiatrist can get samples of those. She can't get samples of older drugs because of policy at the hospital where I go. But cariprazine has a high risk of the same syndrome and Rexulti isn't great for the same risk. So I don't know. We think I really need to come off Seroquel because I'm on a high dose (very high) and it's not working like it used to but what to try is a very big question.

Avoiding trying another old drug or the new drugs is one of the reasons I'm possibly doing ECT.

I looked it up and 1-6 mg is the target dose of risperdal for bipolar so you're pretty much in the middle. And as others said 100 mg of Seroquel is quite a low dose, often prescribed for sleep more than for full antipsychotic effect.

2 APs are NOT FUN though so hopefully someday you won't need both.