I was prescribed and have been taking Seroquel for the past 2 1/2 -3 weeks and it has immensely helped with halting my mania and stabilizing my mood. However, I have an insatiable appetite now, which is bad news. I did the same thing with Depakote and gained 90 pounds in less than a year on Depakote. I DO NOT want a repeat with Seroquel as it has taken literally 5 years to lose 30 pounds from my "Depakote debacle". I'm going to talk to my pdoc's nurse tomorrow to request to be taken off Seroquel & put on something else that doesn't cause increased appetite and rapid weight gain. Any ideas of something to request that will level out moods & not cause the weight gain issues?