I couldn't take lamictal because it gave me a rash, and the first time I tried Latuda was when I was still very deep in my eating disorder so I couldn't really take it (you have to take it with food, preferably about 300 calories, and I was eating a total of maybe 500 calories a day)...but now that I'm in remission, I find Latuda to be extremely helpful. I've been on it this second time around for months now, and I wouldn't change it for anything. Not once have I even gotten hypomanic while on it. I did hit a deep depression when my Zoloft pooped out on me after 2 years of service, but a change in meds to Wellbutrin fixed that up real quick!