I haven't been on Latuda but it does seem rather common for people to need med adjustments and changes from time to time.

Meds don't make the bipolar go away they just lessen it so if you're having a bad flare up it might flare up right through the meds. You may need something else or more latuda even in just the short term to get through this episode. Doesn't necessarily mean it "stopped" working. Does that make any sense?