I used to take zoloft as monotherapy. I married someone after knowing them a week and then proceeded to rapid cycle my way through the year...but did help a lot with anxiety! and hey, I'm still married more than a year later, so it couldn't have been that bad I did have a terrible time getting off of it, experienced withdrawal symptoms (dizziness and head-zaps) for months. I'm really sensitive to meds though and I think this is common to basically all psychoactive drugs.