Bilateral, or high-level unilateral, ECT are known to significantly increase the risks of permanent memory loss. I had a course of 22 ECT treatments (7 unilateral, the rest bilateral) over 15 years ago. I experienced permanent and extensive memory loss. I was unable to remember friends, family, significant events, and could not remember enough of my education and training to be able to return to my professional career. It helped treat the depression but came at a very, very high price.