Thanks for your response! I only got up to 75 mg of Effexor XR. I'm pretty sensitive to meds (was only on 15 mg of Paxil before this and, before that had issues on Zoloft when I tried to go up to the regular therapeutic dose). I'm a little concerned that p-doc is starting me on 60 mg of Cymbalta, when she said that 60-90 mg is a regular therapeutic dose. And they're capsules, so I can't gradually move up.

It also doesn't help that I talked to my mother-in-law when we picked up my daughter tonight, and she said Cymbalta made her into a raving lunatic Then again, every drug affects people differently, so I guess I need to give it a shot.

And I do know about withdrawal from SNRIs--she said I shouldn't have to worry about it because I'm going from one SNRI to another. I was on Paxil before this and gradually tapered it down while going up in Effexor and staying on Effexor at 75 mg for a few weeks before stopping the Paxil.

The good thing is I have therapy appointments Monday (marriage counselor, though he's willing to talk about some of my individual issues, since they affect our marriage), Tuesday (individual T), then p-doc Friday. So I should have lots of support, plus my husband is aware of what's going on and has been pretty understanding. I just want the depression and any self-harm or suicidal thoughts (I know they're somewhat different things) to go away. Ideally without any major side effects. Which I feel like is asking a lot...