So I've been on assorted SSRIs for anxiety, the most recent being Paxil. After having some depression symptoms, my p-doc tried Prozac (which I hadn't had before), which helped depression, but sent my anxiety through the roof. So a couple months ago, she had me try Effexor XR. I thought it was helping at first (certainly better than Prozac!) but in the past two months I've been on it, I've had , which is something I haven't had in many years.

Met with p-doc today, and she thinks I'm in a major depressive episode (also very weepy over minor things, etc.) Although there are contributing factors, it could be that the Effexor either isn't being effective or is contributing to the depression/other stuff. She's trying me on Cymbalta. Has anyone had experience with that, particularly if you've also been on Effexor? From what I read, it sounds like a higher risk of some side effects, and lower for others.

One concern is the possibility of liver damage--so guess I need to cut back on beer consumption, which has been a bit of a coping mechanism as of late. But I should be cutting back on that anyway. And if Cymbalta makes me feel better, then I hopefully won't want/need some other coping mechanism (at least not alcohol).

Just nervous--and she's having me just stop the Effexor and start right up with the Cymbalta, since they both act on the same transmitters. Any thoughts?