I get extremely irritable too, especially when in an agitated depression. It's dangerous for me because I have impulses to hurt my son when he irritates me in those states (like push him or grab him really hard). So I try to be by myself until it passes but now as a single mom that's out of the question. Now I do breathing exercises to resist saying/doing something harmful. If someone says something annoying I'll immediately take a huge breath and breathe it out slowly, which gives me some extra seconds to avoid doing my impulse.