I always had severe depression with some anxiety since my early 20's. During my 5th month of pregnancy all hell broke loose. I had such severe anxiety and OCD and intrusive thoughts that I never slept and never ate. Finally the doctor put me on Paxil and some Xanax because they thought that was better than the other. It was horrible. I had people come stay with me when my husband wasn't home. I was on the phone with my therapist everyday. As soon as I had my baby I just had a little PPD, but was back to normal. Hormones affect everything! I also have Hashimoto's and it affects it all as well. I was only newly diagnosed this past June with Bipolar. BTW, this was 14 years ago and I ended up only having one child and a lot of it was due to that.