I have to admit that I have a great fear that I'll come off Seroquel, lose a lot of weight and then re-gain it as my clozaril dose is increased. If we don't get rexulti samples in the next 3 weeks of course. Then I'll be going down on Seroquel but staying on it and that should be interesting since I made it to 160 while on 600 mg of Seroquel. It's 800 mg or above that my metabolism stops. Inetestingly always at 213. I've rarely hit 215 and never stayed there but 213 has been predictable for severeal years until this summer of weird nutrition and poor appetite.