I think it depends on the work environment and also how much general life experience most of the coworkers have.

Like I once worked in an office environment where things were often pretty boring, so a lot of people were into gossip and drama, forming cliques and conspiring with each other, etc. Also most of them were the sort of people who had lived relatively "normal" carefree lives (with some secret special exceptions, I am sure, since you never know). But anyway so they had a higher tendency to actually give a damn about insignificant things.

However my current work environment is totally different. For one it is busy and stressful as all hell, so frankly anyone who is willing to work hard and help others out is highly valued. We all rely on each other heavily and have to hold together our camaraderie just to make it through a shift. Aint nobody got time to worry about how Cindy talks funny or Jerry's pants are too small. In addition most of us have come from tough walks of life. A single mother of two desperately trying to make ends meet. A young lesbian who has been ostracized by her family and trying to put herself through college with no family support. A woman who has lost multiple immediate relatives to cancer in recent years. Me with my plethora of mental illnesses and history of child abuse. Etc. We are all a little bit wiser than average having been through lots of **** and know that little personality quirks don't matter, we are all good, hard-working people in it together.

So I think more often than not, different places are gonna be different. And if you're in an environment full of people who are bored and privileged enough to freak out over someone being a little socially awkward, well that's the environment, just carry on.