Hey hon, I'm sorry, I get you. When I'm depressed...sure I'm out of mind, but I wouldn't call it derealization because it feels different...I guess that's because I'm too down and out to really notice or even care.
When I have an onset of DP/DR, it's usually triggered from anxiety, stress, drugs, or over stimulation of sensory inputs. I've gotten used to just automatically trying to ground myself by focusing on surrounding objects, describing them, feeling them, reading, to try and make them real.
Or I just sit and go with the flow and let it run its course because I'm used to feeling dissociated, detached, or not in control.
But, a permanent feeling of DR? That has to be awful. Being drugged induced has to make it unshakeable that you would have to wait for the drug to wear off. Hopefully things will get better for you when the lithium wears off.
The Lamictal that I take seems to be side effects free for me, maybe worth trying? Good luck!