Since my last appointment, I've been on 200 mg Seroquel at night (its also SUPPOSED to help me sleep, which it no longer does) plus 40 mg Celexa and 25 mg Seroquel when I wake up. My p-doc already mentioned last month that if the 225 didn't work, we'd probably try something else. I feel crazy... and going through what I've been rehashing with the therapist IS NOT helping matters.