Hello x123: No, I can't say that I have experienced abrupt changes in libido. At this point in my life (which is admittedly older) I have none. Along the way I had prostate surgery which pretty-much destroyed what little physical ability I had left. And this, along with my life-long gender identity issues, depression, & anxiety, plus the effects of antidepressants, pretty-much wiped it all out. Personally I glad it's gone... The older I get, the more the whole process just disgusts me...