Started old time ap in 1970. After a few years off for around 6. Back on fairly steadily until now. Just got back on after a 2-3 year break. Nothing else will keep me approaching stability. I do not go psychotic. Am on other psych meds. Just doesn't work without the ap or the ad. Been on ssdis since mid 1980s. So definitely have been on both types of meds long term. Not having problems with them now. Due to changes in body metabolism being a senior now and having become more sensitive to meds my dosages are lower. But obviously I have no concerns about long term effects. How long does long term define? I can't live without the meds. Nothing else works. So be it. I am on a lot of meds for regular medical problems too. Am not going to worry about them either. My docs try their best to keep up on med interactions with all of them but there is so much unknown there too. Not worried about that either. All I care about is to be able to have a life I can live n do what it takes to maintain it for as long as I can.