I've done lithium (toxicity 4x), zyprexa (tardive dyskensia), depakote (burning in ears/heartburn, lost hearing), latuda (tardive dyskensia), seroquel (slowed heart rate and stopped breathing often), risperidone (panic attacks), oxcarbazipine (didn't do anything), trazadone (severe stomach pain), lamotrigine (migraines), and a concoction of other add ons. Currently using lithium 900 mg with Saphris. Saphris, other that tasting nasty for a few minutes, has been great for no side effects. I've been on it at 20 mg for a little over 2 months and haven't had any bad effects.