I have had treatment resistant depression for 16 years. I am 30 years old. I've tried dozens of medications, and none could get the wishes for death out of my head. Then I tried a new med about a month ago: Adderall. This has been the most amazing month I've ever had. The depression has lifted, and I feel like a normal person! My T says the difference is night and day! If you haven't tried it, it might be worthwhile to test it out. I take 15 mg XR. Best wishes...