Sorry, should have added more details.
I'm at 150 still, it's the Welbutrin XL that I guess is delayed release? I'm taking it for depression and anxiety, the depression has been worst lately. I think I may have SAD, I seem to get depressed every winter, though it happens other times as well.
Not on any other meds except birth control, dunno if that matters. Could have an effect on hormones I guess. I have actually discovered that birth control tends to improve my mood. Did an experiment a couple years back, stopped taking both birth control and Zoloft at the same time, then tried them separately. I found that on just Zoloft, my mood wasn't very good and I had decreased libido. On just birth control, I felt a little better and the libido issue disappeared. But I've been on birth control consistently for more than five years now, and it isn't enough for my mood anymore.

I've tried Lexapro before, but it was years ago. That one didn't seem to have much effect on me at all.
Prozac, on the other hand, I think made me more prone to rage. I guess it's possible I was just going through a natural period of rage and it wasn't related.
Cymbalta was ineffective.
Seroquel and Trazodone, as I've mentioned, had terrible side effects, and I think it was also when I was taking those that I became dependent on my pills to sleep, and it took years to re-train myself to sleep on my own.

Those are all the anti-depressants I can remember, though I've also taken anti-anxiety meds. I was prescribed Xanax (real Xanax) at age 12, before they stopped giving them to minors. I wonder if it somehow messed up my neurons or something. I did manage to stop taking them before becoming dependent, because I started noticing a placebo effect. In the past few years I've also sporadically taken Klonopin. Haven't in months though, I'm actually out right now and my doctor didn't want to refill it for some reason. I was using the online refill service and the nurse wrote me back and was really vague about the reason. I was too lazy to press the issue, since my anxiety has been pretty manageable lately.

It looks as though I've never been on a TCA though. I wonder why no doctor has ever suggested them to me?

I just learned something interesting, regarding hormones. I am NOT a morning person, never have been, and in fact experience morning sickness many mornings, and have since childhood. I looked this up just now and found that it's rather common, and common causes include acid reflux and the body's inability to release serotonin or adrenaline in the morning. But only for some people, and that's why most people don't feel like they're dying every morning.
Here's what gets me: if it is a lack of serotonin, shouldn't an SSRI help? Come to think of it, I can't recall if I had these symptoms when I was on SSRIs. I don't really know the actions of dopamine and norepinephrine, which the Welbutrin is a reuptake blocker for. But is it possible that it's actually making my morning symptoms worse?

Well crap. I also just learned that I should have been taking my Welbutrin in the morning, not at night. I've been taking it at night for three months. Do you think I have to do a whole 3 months more taking it in the morning to see if it works?