My pdoc tells me the clozaril is less sedating than Seroquel. But I'm going to be increasing much more slowly than you, especially at first, and I know that each increase will bring sleepiness. I know my pdoc wants the taper to be slow until they are sure my body is ok with the med b/c I've had so many bad reactions but after the way I'm coming off Seroquel they may want to go up faster just to get me some rest and a break from what I'll be going through. But overall I guess it should settle into a sedating but not extremely so drug. (My target dose is also a bit lower, 200 mg since I'm going to keep my other meds except maybe lithium and let them boost it instead of going off those and letting Clozaril do all the work. She's hoping that will prevent problems. I know it's just a guess though since I always under-react or over-react so 200 will be plenty or not even close to enough).

Hope you feel better tomorrow.