I've been rolling along for about 6 months now, no severe highs and lows. Lo and behold about 3 weeks ago I went into mania on a vacation, and forgot to take my morning meds for 3 or 4 days (10mg lexapro and 75mg seroquel) mania escalated and then last Friday I went spiraling into a depression that I cannot deal with. I have an appt with Tdoc tomorrow and Pdoc on Friday. I was in hospital in Feb/March for 4 weeks to find and tweak a med combo which eventually ended up as : 10mg Lexapro & 75mg Seroquel in the a.m. and 200mg Lamictal & 300mg Seroquel in the p.m. I am now not taking the prescribed dose of Seroquel as i am tired of feeling like a zombie in the a.m. This is what I do, I fu*&*ck with my meds and think I am a doctor. However, I did sleep at a Holiday Inn Express last night. I want to get off all meds and start over. I guess I just needed a place to vent, no gifts please.