I don't really remember any side effects of Latuda, but there was an adjustment period for sure. Now I just make sure I eat enough before taking it so I don't get sick, but that's the only thing I have to worry about. And I've found that it doesn't have to be a meal, eating something like a yogurt is enough. I know they say take it with 350 calories, but as an anorexic, that's a complete no-go, and it works just like it's supposed to with me not doing that.