Yes - not 100% but almost. My mother explained this to me when I was little and she was teaching me genetics - I remember she said colors in cats are carried on the X chromosome, so you can only get the range of colors you see in calicos in female cats. So male calicos must be a kind of mutation - have two X chromosomes or something.

Eta: and then a female ginger would need to have two ginger X chromosomes instead of 1, so odds are they won't. My grandmother had a female ginger - easily my least favorite cat ever, personality-wise.