Whether lithium is working depends on your blood level, not your dose. So that's the first question (which would obviously require your pdoc to order labs; they are usually very good at doing lithium levels on request because they don't want to miss anything). The other thing is that they may start to work but you might still need more for it to REALLY work. 10 mg of Zyprexa is (I think) a medium dose so maybe you need a little more. Or maybe Zyprexa doesn't work for you. It doesn't even make me sleepy, much less have any other effect. It works well for most people but not everyone is most people. Regardless I'll get in touch your pdoc just to touch base and let him know you are feeling more manic, not less and is there any adjustment that can be done? I am still asking that in messages to my pdoc even though I know there aren't, just because I think it justifies contacting them (and I know she doesn't care and I don't need the excuse but it makes me feel better).

Rarely a med does have the opposite effect. I've not heard about that too often with Zyprexa. I suppose it could have happened to me but I was so extremely agitated when I went on it that I'd not have known. I just know it did not help. I've had a med or two that should have made me tired and did the opposite. Benadry is one; in the hospital after Zyprexa (plus a heap of Seroquel and other sedatives) didn't work and we were waiting for me to see a psychiatrist b/c I came in over the weekend they were giving me Benadry every 4 hours until about 30 hours into this the nurse realized I got worse with every dose. Obviously they stopped it and traded it for showers and a 1:1 aide until better meds were prescribed. I reacted that way to a mood stabilizer or AP but I can't remember which one. Keppra did it but that was a long time ago and it never made it into being used commonly as a mood stabilizer; maybe that is why. There was another one though. It doesn't really matter which, it just will annoy me until I remember . But that's another reason to touch base with your pdoc tomorrow.