I was medically hospitalized with anorexia just before being put on Seroquel after going through a trauma. Pdoc gave it to me so I could sleep without the nightmares. Used the high dose 600mg on & off a few years until I moved & got a new life. Interesting because it had no effect on my weight though I was finally able to gain back to a healthy weight it took 2 years. Interesting how it didn't effect my weight in the way it does to others....maybe my whole body condition at the time wouldn't allow that effect.