I'm on Seroquel and it has caused pre-diabetes and not by weight gain. This is the third time I've been on it. I've tried I believe all of the APs and have been allergic to most or severe side effects. I tried all those times getting off of a Seroquel because of the diabetes, but it's the only one that works for me. Looks like I'm stuck on Seroquel and diabetes medication. I wish you good luck.