-----As a bipolar, the most important med to take is some kind of stabilizer: lithium or tegretol and there are others. Over time, a stabilizer lessens the ups and downs. Yes, we have to be careful with anti depressants, because they can kick us up too high. I am looking for an answer to this right now for myself. I may switch to lamictal as a stabilizer. Right now I use Ativan when I get hypo manic but the problem with mania is that often you can't see that u r too high until u have caus d relationship problems. I am trying smaller doses of Wellbutrin. It's so individual. Chart yr symptoms to help your doc get the right combination