There are so many different ones out there, but I find the meds themselves only take the edge off. You have to use many coping skills and desire to kick depressions dark scary butt. I know That is really hard to do especially when you are really down. I was about to sign myself back into the hospital yesterday. But I decided to go for a walk and have a talk with myself. I went for a very long walk and had a very long talk. I unraveled many of the hidden parts within myself. I don't feel empty anymore. I've felt empty for as far back as I can remember. There's something to be said for the whole walk thing, I guess I just never walked far enough before. That or I wasn't ready to idk. I've suffered with depression since childhood. I'm not sure it's gone for good, but here's to hoping!