I've actually lost weight since I've been on respirdal. My pdoc put me on a strict diet to stay away from carbs. He told me that if I didn't stay away from them completely, I would crave them even more and I would be back in two weeks cursing him out because of my weight gain. When i've actually stuck too it, i've lost weight. In general, i try to stay away from carbs early in the day. The earlier I eat them, the more I crave. The higher the dosage, the worse it gets. Good luck on finding what works for you. I couldn't use seroquel. I was having side effects that weren't even listed on the list of side effects.