Hi shakespeare
Well kudos to you on wanting distance from those "unhealthy acquaintances/friendships/relationships"

I'd say that firstly you might need to set them some real firm/specific boundaries.........detailing ways of
how their behaviour needs to change...........what you actually expect/want/need from them and the consequences of them not complying. And really use some "
brutal honesty" in that.
Sometimes instinct can be to be sensitive/courteous/considerate (???), but in
some cases that isn't going to be helping the person recognise boundaries.........you're not going to be doing them any favours in the long run.
I know this may be more about positively changing the relationship than disentangling yourself.........but if it turns out from there, that you
do need to disentangle, then it can act as a good baseline in that.
And again in disentangling.........brutal honesty (!!!) and distancing yourself in every which way..........physically, in terms of contact, emotionally..............
Just some thoughts...........
Alison