You don't have to isolate yourself completely, as social skills develop with practice, but you need to work on some basic principles that guard your general behavior in the real and virtual worlds. You don't have to get what you want from the first time, but with time (and practice) you will get what you want. Being genuinely nice all (at least most of) the time is very important. Many people are nice at their core, but this isn't enough. How you communicate it is important as well.

I hate to say this, because I hate doing it myself, but it seems there is no way around it: try to focus on something else other than relationships without isolating yourself completely. Try to improve your skills at work, for example. Being independent and confident in your work is perceived positively by many people. May be this will attract people to you instead of you going to them.