I don't mess with mine too much. I have discontinued Seroquel and Saphris on my own in the past though. I had made up my mind I was not going to take them anymore. Seroquel made me gain weight and Saphris made it too hard to get up in the morning. My pdoc was irritated that I didn't call him first. At one point though I was prescribed too much gabapentin than I felt comfortable with and started taking less. Now he just writes it for less. But he writes it to take 1 to 1.5. He mostly listens to me and writes for meds how I feel comfortable.
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